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About Us

About SineuGene

SineuGene Therapeutics Co., Ltd. is a clinical-stage biotech company pioneering innovative therapies, focusing on AAV-based and nucleic acid-based treatments, for neurological disorders. Founded in late 2021, the company’s initial pipeline was built upon foundational research led by Dr. Yichang Jia at Tsinghua University's School of Medicine. SineuGene leverages cutting-edge technologies, such as adeno-associated virus (AAV) mediated gene delivery and antisense oligonucleotide (ASO) based gene regulation, to develop a robust pipeline targeting central nervous system disorders including ALS, Stroke, Parkinson’s Disease, Alzheimer’s Disease, Multiple System Atrophy (MSA), and Spinocerebellar Ataxia Type 3 (SCA3).

In 2025, SNUG01, SineuGene’s lead program for ALS, received IND clearance from both the FDA and NMPA, as well as Orphan Drug Designation (ODD) from the FDA. The company is actively advancing an international China–US multi-center clinical trial. SineuGene is committed to translating scientific discoveries into transformative therapies for patients worldwide with unmet and urgent medical needs.

Founder

Yichang Jia, Ph.D.

Founder and the Chairman of Scientific Board of SineuGene

Dr. Yichang Jia is the Tenured Professor in School of Medicine and Vice Dean of School of Basic Medical Sciences, Tsinghua University. He is also a Principal Investigator of Center for Life Sciences (CLS), IDG/McGovern Institute for Brain Research at Tsinghua University, and Tsinghua Laboratory of Brain and Intelligence. Dr. Jia got his Ph.D. in Institute of Neuroscience, Chinese Academy of Sciences, and his postdoctoral training in The Jackson Laboratory, Maine. He has employed mouse genetics to study the disease mechanism underlnying neurodegenerative diseases since his postdoctoral training.

Founder

Lin Peng, Ph.D.

Co-founder and Chief Executive Officer (CEO) of SineuGene.

Dr. Peng got his Bachelor and Master in the College of Life Sciences, Beijing Normal University. He got his Public Policy and Management Discipline Ph.D. degree in the Institute of Education?(Mentor, Dr. Jian Lin), Tsinghua University. He was a visiting scholar in the Global Engineering Education Collaboratory (GEEC), College of Engineering, Purdue University (West Lafayette, IN). Dr. Peng worked at the School of Life Sciences at Tsinghua and Westlake Institute for Advanced Study (WIAS). In WIAS, he worked for Dr. Yigong Shi as Dean Assistant to help on setting up of Westlake University. Before joining SineuGene, he was the CEO of Tianyin Health Development Co., Ltd, Nanjing, Jiangsu, China. Dr. Peng's biological background, business management skills, entrepreneurship ensure his leadership at SineuGene.